FCPS Medicine Part 1 Paper II preparation and Syllabus in Bangladesh

FCPS Medicine Part 1 Paper II Preparation & Syllabus


FCPS Medicine Part 1 exam has 3 paper:

  1. Paper 1
  2. Paper 2
  3. Paper 3

FCPS Medicine Part 1 Paper II syllabus and preparation

The Second day of FCPS part- II exam is paper- II exam. Since the paper-II test is done on the Second day, so the preparation can be done very tightly for paper-II, with concentration and seriousness for pass in first times. All in all, the preparation of Paper-2 is more or less good for everyone. So you have to try to get excellent marks in Paper-2.

FCPS Medicine Part 1 Paper II topics

The FCPS Medicine Part 1 Paper II has seven topics :e.g. below following :

  1. Cardiology
  2. Endocrinology and Metabolism
  3. Clinical Nutrition
  4. Toxicology
  5. Dermatology
  6. Psychiatry
  7. Medical Statistics

FCPS Medicine Part 1 Paper II Marks Distribution 

Endocrine and Metabolic Disorder30
Clinical Nutrition 06
Toxicology 06

1. Cardiology for FCPS Medicine Part 1 Paper II

Anatomy and physiology of heart

You should have knowledge of the basic anatomy and physiology of the heart in health and disease: Examples of topics that might be included :


  • Clinically relevant normal anatomy of the heart, coronary arteries and great vessels
  • Determinants of heart rate and rhythm
  • Cardiac function
  • Cardiac condition
  • Cardiac output
  • Vascular tone
  • Blood Pressure
  • Coronary blood flow
  • Genesis of heart sounds 

Pathophysiology and Pathology

You should know the mechanisms underlying the main pathological processes.Examples of topics that might be included :

  • Thrombosis
  • Infarction
  • Atherogenesis
  • Hypertrophy
  • Heart failure
  • Cardiomyopathies
  • Dysrhythmias
  • Hypertension 

Cardiac Cell Biology

  • Excitation-contraction process
  • Molecular and cellular aspects of hypertrophy of the myocardium and of vascular smooth muscle. 

Heart Pharmacology

  • Indication for drug therapy in cardiac disease
  • understand the actions, interactions and side effects of the drugs used in cardiac disease. 
  • The emphasis will often be on new drugs or on novel applications or newly observed side effects of established drugs. 

Clinical Cardiology

  • Chest Pain
  • Clinical features of constrictive pericarditis, 
  • Clinical features of cardiac temponade,
  • Clinical features of endocariditis, 
  • Clinical features of valvular heart disease
  • Management of coronary syndromes
  • Management of cardiac failure
  • Management issues in atrial fibrillation
  • Indications for, and types of, permanent pacemaker

Knowledge of important changes in clinical practice

  • Use of ACE inhibitors after myocardial infarction
  • Use of HMG CoA reductase inhibitors in primary and secondary prevention of coronary morbidity and mortality
  • Use of beta-adrenoceptor blocking drugs in left ventricular dysfunction

You should know :

  • Indications for invasive and non-invasive cardiac investigation
  • Principles of these investigative methods, their limitations and the clinical relevance of the results
  • Knowledge of the practical aspects of the investigative techniques is not required.
  • Common ECG abnormalities
  • Basic echocardiographic abnormalities such as hypertrophic obstructive cardiomyopathy or pericardial effusion
  • Indications for coronary angiography 

2. Endocrinology and Metabolism for FCPS Medicine Part 1 Paper II

Anatomy and Biochemistry

You have no need to have a detailed knowledge of biochemistry, it is anticipated that you will have an insight into the mechanisms of hormone action and the importance of receptors, neurotransmeter and substances involved in control of intracellular action & metabolism. You should have knowledge of the clinically relevant anatomy.
  1. Factors involved in cell signaling Anatomical relationships of the pituitary gland
  2. The cell types in the pancreatic islets
  3. A broad understanding of the pathways of carbohydrate, protein and fat metabolism
  4. Endocrine tests in routine clinical use

Hypothalamus / Pituitary

No need to deep knowledge about Hypothalamus and pituitary. 

  • The physiology and pathophysiology of control of pituitary hormone secretion 
  • The mechanisms of maintaining plasma osmolality
  • Tests of pituitary hormone secretion
  • Pituitary diseases such as acromegaly, prolactinoma and Cushing’s syndrome
  • Drugs used in the treatment of pituitary disease
  • Pituitary replacement therapy


You need to have a broad knowledge of the mechanisms of thyroid disease, its clinical presentation and treatment.

  • Thyroid hormone biosynthesis
  • Thyroid hormone control
  • Important drugs interfering with thyroid function
  • Indications for use of various types of thyroid function tests
  • Autoimmunity and the thyroid
  • Clinical features of thyrotoxicosis and hypothyroidism
  • Goiter and its management
  • Thyroid neoplasia


  • Tests for adrenocortical function
  • Endocrine causes of hypertension and their differential diagnosis
  • Clinical features and management of adrenal hyper-and hypofunction
  • Complications of steroid therapy


  • The aetiology of hypogonadism both primary and secondary
  • Causes of male infertility related to general medical diseases and its treatment
  • Causes of erectile dysfunction and its investigation 
  • Androgen replacement therapy  


  • Control of calcium metabolism
  • Laboratory tests of parathyroid function
  • The causes of hypercalcaemia
  • The mechanisms of osteomalacia
  • Hyperparathyroidism, both primary and secondary
  • The prophylaxis and treatment of osteoporosis

Diabetes mellitus 

You need to have broad knowledge About Diabetes mellitus. 
  • Control of carbohydrate metabolism
  • Aetiology of type 1 diabetes and type 2 diabetes
  • Insulin resistance
  • Management of diabetic emergencies
  • Diabetic Complications (Peripheral Neuropathy, Diabetic foot ulcer, Diabetic Retinopathy,Diabetic Ketoacidosis,Hyperosmoler nonketotic coma, Hypoglycemic coma,hypoglycemia and hyperglycemia) 

Disorders of lipid metabolism

  • Control of cholesterol metabolism
  • Etiology of different types of hyperlipidemias including both cholesterol and triglyceride disorders
  • Indications for lipid lowering agents and their complications


You should be familiar with:

  • Nutritional requirements in health
  • Assessment of nutritional status
  • Nutritional deficiency states
  • Primary nutritional disorders
  • Calorific requirements
  • Body water distribution
  • Derivation of the body mass index
  • Protein calorie malnutrition
  • Essential dietary constituents
  • Vitamin requirements
  • Pathogenesis and management of obesity


You should understand the principles of management of patients who have been poisoned or toxicated with drugs or other toxic,poisonous substances. This should include assessment, recognition of common symptom patterns, principles of removal of toxic substances, and their antidotes where these approaches may be appropriate.

  • (OPC)Organophosphorus poisoning
  • Atropine/datura poisoning
  • Ethanol poisoning
  • Methanol poisoning
  • Benzodiazepine poisoning
  • Tetrodotoxin poisoning
  • Snake bite



Mental state
You should understand the conduct and scope of a mental state examination.
You are expected to be familiar with features of abnormal mental states and particularly those that present commonly to physicians and to Accident and Emergency Departments.

Etiological factors in psychiatric illness
You should understand the primary etiological factors in psychiatric areas including:

  • Genetic factors
  • Environmental factors
  • Life events
  • Investigations

You should be familiar with the potential value of,Symptoms,diseases and indications for common laboratory procedures used in psychiatric illness including:

  • Psychometric testing
  • EEG
  • Brain imaging
  • Syndromes of psychiatric disorders and their treatment You should have knowledge of Organic brain syndromes (delirium, dementia, focal brain syndromes, head injury)
  • Schizophrenia and related syndromes
  • Paranoid disorders and related syndromes
  • Affective disorders (anxiety states, phobic disorders, bipolar affective disorders)
  • Grief and bereavement
  • Self-harm, attempted suicide, suicide
  • Substance misuse (including alcohol dependence)
  • Eating disorders
  • Obsessive compulsive disorder
  • Abnormal illness behavior
  • Syndromes associated with medically explained physical symptoms (including somatization and somatoform disorders)

Psychiatric aspects of physical disease You should be aware of the psychiatric presentations of physical disease including:

  • Endocrine and metabolic disorders
  • Toxic states
  • AIDS
  • Neurological disease
  • Epilepsy
  • Pain
  • Mental retardation


Basic Science


  • Anatomy and  structure and  of the epidermis and dermis.
  • function of the epidermis and dermis.

Clinical Dermatology

Knowledge of the clinical features of the following skin diseases is required:

  • Psoriasis
  • Eczema
  • Urticaria
  • Superficial fungal infections (dermatophytosis, pityriasis versicolor)
  • Common skin cancers such as melanoma
  • Vitiligo and alopecia areata
  • Pemphigus and pemphigold
  • Cutaneous herpes virus infections (herpes simplex, varicella zoster)
  • Cutaneous staphylococcal and streptococcal infections
  • Leprosy

cutaneous signs or symptoms which may indicate internal disease:

  • Itch
  • Hyperpigmentation
  • Generalized erythema
  • Loss of hair
  • Increased hair growth
  • Common patterns of nail dystrophy such as clubbing
  • Erythema nodusum
  • Erythema multiforme
  • Purpura
  • Ulceration
  • Vasculitis

cutaneous symptoms and signs of systemic diseases.

  • Collagen vascular disease such as SLE, systemic sclerosis
  • Metabolic and endocrine disorders
  • Infectious diseases
  • Cancers
  • Leukaemias
  • Respiratory and cardiovascular diseases
  • Common inherited diseases such as neurofibromatosis
  • Dermatological complications of the Practice in Therapeutic immunosuppression (for example, systemic corticosteroid therapy, cyclosporin etc).
  • diseases such as HIV which cause immunosuppression.


  • Important investigation

 Drugs and therapy

  • drugs for dermatological treatment,
  • Side effect of Drugs which cause life-threatening skin conditions such as erythroderma or Stevens-Johnson syndrome, angio-oedema and toxic epidermal necrolysis.


You should have a basic understanding of the usage and limitations of the common statistical tests used in reporting the results of research in clinical journals. The following lists of terms should give some idea of the range of terms and techniques which you should understand, all of which can be found regularly in journals such as The Lancet, British Medical Journal and New England Journal of Medicine.

You are not expected to have any knowledge of computer packages for carrying out statistical calculations. You may be expected to carry out simple calculations that do not require the use of calculator. You are not expected to memorise formulae for statistical tests, but should understand their conceptual basis.The following lists are not intended to be inclusive but as illustrative of the type of knowledge that you need to inclusive but as illustrative of the type of knowledge that you need to possess.

Descriptive Statistics

Examples of topics that might be included:

  • Mean, median, mode
  • Standard deviation, standard error
  • Confidence interval
  • Variance
  • Range, quartile, inter-quartile range
  • Percentile
  • Skewness
  • Contingency table
  • Population
  • Missing values
  • Outliers

Graphical techniques

Examples of topics that might be included :

  • Histogram
  • Box-plot
  • Scattergram

Inferential techniques

Examples of topics that might be included :

  • Null hypothesis
  • Alternative hypothesis
  • Parametric and non-parametric tests
  • Normal distribution
  • Type 1 and Type 2 errors
  • False positive and false negative
  • Statistical power
  • One and two-tailed tests
  • Statistical significance, P value
  • T-test • Mann-Whitney and Wilcoxon test
  • Chi-square test for 2 x 2 contingency table
  • Correlation (Pearson’s and spearman’s)
  • Linear regression
  • Study design


Clinical trials


Examples of topics that might be included :

  • Interpretation of simple clinical trial data
  • Randomization
  • Placebo-controlled trial
  • Open trial 
  • Single-blind trial
  • Double-blind trial
  • Intention-to-treat
  • Bias
  • Evidence-based Medicine
  • You are expected to have an understanding of evidence-based Medicine and an ability to apply this understanding in the management of patients  
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Edited by, 
CEO of Doctors Gang
MBBS(Rangpur Medical College). 
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