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Third professional MBBS Examination Question Bank | Microbiology|Pharmacology| Pathology | Doctors Gang

Third professional MBBS Examination Microbiology Question Bank under Rajshahi University 

Third professional mbbs question Bank


Third professional MBBS examination Question Bank and Suggestions 

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Microbiology Question Bank

1. RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2019
Subject: Microbiology

Full Marks: 70
Time: 2 hours 40 min
(NB Marks for each question are shown in the margin. Answer any 4 questions from each group including question No. 5 which is compulsory.
USE SEPARATE ANSWER SCRIPT FOR EACH GROUP)

Group - A

  1. State the differences between eukaryotic and prokaryotic cell. What is selective toxicity? Discuss the basis of selective toxicity for penicillin.
  2. Define sterilization. Give principles of autoclaving. Outline the steps of diagnosis of bacterial diseases.
  3.  What is virion? Mention the structures of virion. Statet the stepsof viral replication
  4. Name the vector brone viral diseases. Write down the pathogenesis and diagnosis of dengue haemorrhagic fever.
  5. A clinically jaundiced patient has been referred for viral etiologycal diagnosis. What are the laboratory tests will you perform? What may be the diagnosis?
Group - B
  1. Define and classify host. Name parasites causing anaemia. Describe the pathogenesis of hepatic amoebiasis.
  2. Mention the species of leishmania and diseases produced by them. What is PKDL?How can you diagnose a case of malaria in laboratory?
  3. Give the differences between cestodes, nematodes and trematodes. What are the pathogenicities caused by ascaris lumbricoides?
  4. Name the fungal spores. Give the laboratory diagnosis of dermatophytes.
  5. A 4 years old boy came with the complains of perianal itching specially at night. Which 2.5may be the parasitic cause? How can you diagnose the parasite?
Group - C

  1. Name four important pyogenic bacteria, Write down the important toxins and enzymes produced by staphylococcus aureus. 
  2. Write down the role of coagulase enzyme of this organism, Mention the important properties of mycobacterium. Give the laboratory diagnosis of an open case of pulmpnary tuberculosis. Why multidrug treatment for prolonged needed to cure the infection?
  3. Name four important spore bearing organism with their disease produced. Write down the pathogenesis of tetanus and prevention of tetanus.
  4. Name the important bacteria causing urinary tract infection. How you proceed to diagnose a case of UTI if it is caused by Esch. Coli? Mention for important general characteristics of Esch. Coli.
  5. A 5 years old boy compains high fever, neck stiffness, headache and vomiting for 3 days. What will be the probbale diagnosis of you? How can you confirm your diagnosisin a laboratory?
Group - D


  1. What is innate immunity? Discuss the cardinal features of acquired immunity. How does B-cell activate?
  2. Define immunoglobulin. State the classification and development of T-lynphocytes.Mention the function of natural killer cells.
  3. Define transplantation. State the classification of grafts. What are the tests done to check tissue compatibility?
  4. Mention the major uses of serological tests. Write down the complement deficiency diseases. State briefly pathogenesis of rheumatic fever
  5.  A young man treate with penicillin and after few days develops fatigue., weakness and shortness of breath. He had no history of penicillin hypersensivity. Blood film shows hypochromia ad lytic feature of RBC. What is your clinical diagnosis? What laboratory test you suggest to do?

2. RAJSHAHI UNIVERSITY
THIRD PROFESSIONAL MBBS (May) EXAMINATION, 2019
Subject: Microbiology

Group - A
  1. Classify spore forming bacteria. What is sporulation? Why spore is more resistant than vegetative form?
  2. What is Koch's postulate? What are its limitation? How it can be overcome?
  3. What is cytopathic effect? Write in brief about interferon. Name slow viral disease with causative agents.
  4. Mention different seromarkers of hepatitis B viruses with their importance. State post exposure prophylaxis of rabies.
  5. A woman of 18 years, having history of nlood transfusion develop fever, nausea,jaundice, elevated transaminase level. What may be the diagnosis? How such disease can be prevented?
Group - B
  1. Enumerate the tissue nematodes and describe the pathogenesis of classical filariasis.
  2. Classify protozoa according to their organ of locomotion with examples. Write down the laboratory diagnosis of visceral leishmaniasis. What is Black "water fever'?
  3. Classify fungus according to their morphological form with examples. Mention the prerequisite factors responsible for opportunistic mycosis.
  4. Mention the important properties of cestodes. State the pathogenesis and laboratory diagnosis of hydatid cyst in human.
  5. A child bearing lady noticed excessive foul smelling vaginal discharge for last 10 days with itching and dyscareunia. What will be the differential diagnosis of the case?Name the test to confirm diagnosis.

Group - C

  1. Classify streptococci with example. List toxins and enzymes of streptococcous pyogens with their role in pathogenesis. What is the significance of M protein?
  2. List bacteria that do not readily take Gram-staining with important diseases caused by them. Give laboratory diagnosisof primary syphilis with a special note on VDRL test.
  3. Name bacteriae causing meningitis in different age groups. State the laboratory diagnosis of suspected case of meningitis by H. Influenzae. Write down the importance of bacterial polysaccharide capsule. 
  4. Name medically important Gram-positive rods with diseases caused by them. State the pathogenesis and manifestations of botulism. Write a note on botalinum toxins.
  5. A young man complains of initial low grade fever that later became step ladder during 2nd week. Clinical examination reveals bradycardia and there is leucopenia in complete blood count. What is your provisional diagnosis? What is the common serological test and its expected findings in this case?
Group - D

  1. Name the components of innate immunity. Define Hapten and Immunogen. Describe the criteria of good antigen.
  2. Define MHC. Mention distributionand biological importance of MHC antigen.
  3. Draw and label the structure of Immunoglobulin molecule. Mention properties of IgG and IgM
  4. Classify hypersensivity with example. Explain the mechanism of type-1 hypersensivity with diagram
  5.  A 26 years male tested in skin with purified protein derivatives (PPD), developed an induration of 15 mm after 48 hours. What is your interpretation? Mention the type of reaction. Name the cells responsible for such induration.

3. RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (May) EXAMINATION, 2018
Subject: Microbiology

Full marks: 70
Time: 2 hours 40 min
(NB: Marks for each question are shown in the margin. Answer any 4 questions from each group including question No. 5 which is
compulsory. USE SEPARATE ANSWER SCRIPT FOR EACH GROUP)

Group -A

  1. Define bacterial growth. Mention the nutritional and environmental requirements of bacteria. Describe the importance of lipopolysaccharide.
  2. Give the structure of an endospore. Mention the process of spore destruction in a laboratory.How bacteria become resistant to antibiotics?
  3. Name the vector borne viral diseases. Write down the pathogenesis and diagnosis of Dengue. haemorrahgic fever?
  4. Mention the basic structure of a virus with function of them. What measure will you take after bitting of a rabid animal?
  5. A male person of 27 years old with a history of intravenous drug use. What will be probable.
  6. infection of him along with their complications.

Group - B

  1. List the diseases produced by different species of leishmania and plasmodium. Give the laboratory diagnosis of PKDL. What is premonition?
  2. Write down the differences between cestodes and trematodes in tabulated form. Discuss the pathogenesis of diphylobothriasis.
  3. Give the characteristics features of occult filariasis. Mention the peculiarities in the life cycle of strongyloides stercoralis. What is auto infection?
  4. Name the systemic and opportunistic mycotic agents. Write down the laboratory diagnosis of dermatophytoses. What is germ tube?
  5. A 30 years old female complains of excessive foul smelling vaginal discharge with itching and dysparunia. What is your provisional diagnosis? How will you proceed to diagnose such case?

Group - C

  1. State the pathogenesis of pneumonia causes by S. Pneumoniae. Give the laboratory diagnosis of bacterial meningitis. What is ASO titre?
  2. Mention the common properties of enterobacteriacae. State the pathogenesis of enteric fever.What is ESBL?
  3. Name five bacterial cause of diarrhea. Write down the mechanism of cholera. Give the laboratory diagnosis of sore throat.
  4. Enumerate the pigment producing bacteria. Describe the pathogenesis of Cl. Myonecrosis.Write down the laboratory diagnosis of primary syphilis.
  5. A patient has a history of low grade fever, persistent cough for 3 weeks and loss of appetite. 
Group D
  1. Define Hampton, allergen and adjuvants. Write down the important features of adaptative
    immunity. What is pattern recognition receptor?

  2. Write down the subsets of T-lymphocytes.. How B cells are activated? State the functions of IgG and IgA?

  3. What do you mean by positive selections, negative selections and MHC restriction? Write down the pathogenesis of haemolytic disease in newborn.

  4. Name the initiators of alternate pathway of complement activation. Explain molecular mimicry and epitope spreading as mechanism of autoimmunity. What is DiGeorges syndrome?
  5. A young female complains of multiple joints pain yielded positive result in Ra and ANA test. 2.5
    What is your clinical impression and what is your next advice?

4. RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2018
Subject: Microbiology

Group - A

  1. Name virulence factors of bacteria. Give the differences of cell of gram positive and gram negative bacteria. Briefly describe the importance of capsule of bacteria.
  2. What is selective toxicity? State the mechanism of action of antimicrobial drug with example,
  3. Mention the mechanism of drug resistance.Write down basic structures of virus. Give diagrammatical representation of steps of viral replication. What is hard immunity?
  4. What is viral load? Mention opportunistic infections in AIDS patients with their causative organism. Name some anti HIV drugs.
  5. A children of 6 years developed yellowish sclera, nausea, dark urine-elevated SGPT. What is your probable diagnosis? How you can diagnose and prevent such a case?

Group - B

  1. What are the morphological forms of Entamobea histolytica? State the pathogenesis of intestinal amoebiasis. Give the laboratory diagnosis of amoebic liver abscess.
  2. State important properties of tramatode. How you differentiate T. saginata and T. solium. 1+2What is Schistosomiasis?
  3. Enumerate parasites that enter through skin penetration. State the pathogenicity produced by A. duodenale. How anaemia occur in ancylosmiasis?
  4. Classify fungus according to anatomical location. State the comparison between bacteria and Fungus. What is mycotoxicoses?
  5. A 30 yrs old male is admitted in hospital with H/O prolonged low grade fever,hepatosplenomegally, lymphadenopathy and pancytopenia. What may probable parasitecausing the disease? How you can diagnose such a case?
Group -C( Systemic Microbiology) 

  1. Name four important pyogenic bacteria. Write down important toxins and enzymes produced by staphylococcus aureus. Mention the role of entrotoxin produced by it.
  2. Name four important spore forming bacteria along with their pathogenesis. Write down the pathogenesis and prevention of tetanus.
  3. Name the disease produced by Esch. Coli. Mention different diarrhoeagenic strain of it. How you proceed to diagnose UTI causes by Esch. Coli?
  4. Mention the special properties of mycobacterium. Give the laboratory diagnosis of a open casebof pulmonary tuberculosis. Why multidrug treatment for prolonged period needed to cure thebinfection?
  5. A 30 yrs old man complains an ulcer in the penis, which is painless and discharging. What will be the probable diagnosis of you? How you can confirm your diagnosis in the laboratory procedures?

Group - D

  1. Classify immunity with example. Compare and contrast between B and T lymphocyte.Name professional antigen presenting cell. Trace the pathway of humoral immune response against protein and polysaccharide antigen.
  2. Define and classify hypersensitivity. Write down the mechanism involved in type-II or cytotoxic sensitivity and give example.
  3. What do you mean by antigen and epitope? What is Fab and how it is formed? 
  4. State the biological function of activated complement component.
  5. A young woman complaints of seasonal shortness of breath, cough with tightness in the chest and admits a family history for her condition. What is your clinical impression? What are thedifferent preventive and therapeutic measures for her condition?

RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2019
Subject: Pharmacology and Therapeutics



Group - A
  1. Enumerate five (05) common routes of drug administration with examples. Write down the advantages and disadvantages of intravenous route.
  2. Name the Hi receptor blockers with indications. What are the expected advantages of generation H, blockers over first generation?
  3. Enlist some important NSAIDs. Explain the analgesic mechanism of diclofenac with indications.Explain with examples how pathological conditions and genetic factor modify drug actions.
  4. Mention the drugs used by inhalation route in the treatment of bronchial asthma. Briefly discuss the bronchodilation mechanism and adverse effects of salbutamol.
  5. Write short notes on: ) Prodrug (11) Type-B adverse drug reaction.
Group - B
  1. Enlist anxiolytic drugs. Write down the mechanism of action and indications of diazepam.What do you mean by preanesthetic medication? 
  2. Name the drugs used for this purpose with rationale,Enumerate the drugs usee 2 diabetes mellitus. Write dwon the role of netform case. Give, lisadarse effects
  3. Enust the drugs used to cred cate H. pylori infection. How misoprostal protect gastric mucosa
  4. Write down the indications of pantoprazole
  5. 5.What are the principal guideline for prescribng antiepileptic drugs? Mention the adverse efectes phenyton.
  6. White short notes on: (1) Ondansetron (1) Escitalopram
Group -C

  1. Write down the biosynthesis of acetylcholine. Name the indirectly acting cholinergic drugs. Why acetylcholine is not used clinically?
  2. Name the drugs with positive inotropic effect used in CCF. Discuss the role of ACE inhibitors dig heart
  3. Enlist the potasium losing diuretics. Write down the mechanism of action and adverse effects of spirononolactone
  4. What options are available for the management of gestational hypertension? How alfa methyldopa acts Mention its adverse effects.
  5. Enumerate alfa receptor blocking drugs with indications. Tamsulosin is preferred over prazocinin explain
  6. Write short notes on Neuromuscular blockers (0) HMG-CoA reductase inhibitors.
Group - D
  1. What the drugs used in UTI. Mention the indications arid adverse effects of ciprofloxacin.
  2. Enumerate the tissue amebildes. Outline the pharmacotheapy of amebic liver abscess.
  3. Name anticoagulants used in vivo. Mention the advantages of LMWH over standard one.
  4. Define and mention the criteria of essential drugs (Eds). Write down the number of Eds used in
  5. different health sector levels of our country,
  6. Justify the combinations (1) Amoxicillin and clavulinic acid (i) Isoniazid and it's
  7. write, short notes on: () Radical cure of malaria (0) Fluconazole.

RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (May) EXAMINATION, 2019
Subject: Pharmacology and Therapeutics

Group - A

  • Name different processes of drug absorption Explain how pH of absorptive face ances drug absorption from gut
  • Outine the biosynthesis of eicosanoid with drugs acting in different step inhibiting the State the therapeutic approach of prostaglandins in gynaecology
  • Elaborate the role of glucocorticoids in acute and chronic bronchial asthma Discuss in bner the role of montelukast in asthma.
  • Mention the olecular targets for drug action. Explain drug enzyme interaction
  • Enumerate  five commonly used non selective cox inhibitors. Mention the consequences of COX-I inhibition with uses of low dose aspirin with justification
  • Winte short notes on Physiological & Pharmacological antagonism (t) Order of kinetics.

Group - B

  • Name the opoid receptors and endogenous oplopeptins. Outline the difference between morphine and mependine.
  • Mention the advantages of atypical antipsychotic with typical drugs. Write down the adverse effects of chlorpromazine.
  • Write down therapeutic approach of a diabetic patient ages 10 years with explanation 
  • Mention the effects of insulin on skeletal muscle and adipose tissue.
  • Compare and contrast ondansetron, promethazine and domperidone with respect to theirmechanism of action and clinical uses.
  • Name the antithyroid drugs. Explain the mechanism of action of any of them with uses
  • Write short notes on: (1) Prediabette 00 Topletherapy

Group-C

  • Name the atropine substitutes with their clinical uses. Mention and justify the use of andote atropine po soning
  • Enlist antanginal drugs. Explain how nitroglycerine relieves angina pain?
  • Define ciuretics and classify them according to their efficacy. Give differences between fruserude and thiazide. 
  • Write down the biosynthesis and fate of adrenergic neurotransmitter. Mention the clinical uses of adrenaline
  • Mention five antihypertensive mechanism and indications of amlodipine.
  • Write short notes on: () Atorvastatin (ii) Neostigmine.
Group - D

  • List the drugs that are used in enteric fever and them which are safe in pregnancy. Explain the mechanism of action of any one of them.
  • Name the haematinics. Give the adverse effects of parenteral iron therapy. Mention the role of folic acid in pregnancy.
  • what do youmean by RUD? What are the impact of irrational prescribing?
  • Cassify tetracycline according to mechanism of action and write down their clinical uses. Why not indicated in case of young children?
  • What are the rationale of combining imipenem with cilastatin and sulfamethoxazole with trimethoprim
  • Write short notes on: (1) Fluconazole (ii) Superinfection,

RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (November) EXAMINATION, 2019
Subject: Pharmacology and Therapeutics

Group - A

  • Enumerate five (05) common routes of drug administration with examples. Write down the advantages and disadvantages of intravenous route.
  • Name the Hi receptor blockers with indications. What are the expected advantages of generation H, blockers over first generation?
  • Enlist some important NSAIDs. Explain the analgesic mechanism of diclofenac with indications. 
  • Explain with examples how pathological conditions and genetic factor modify drug actions.
  • Mention the drugs used by inhalation route in the treatment of bronchial asthma. Briefly discuss the bronchodilation mechanism and adverse effects of salbutamol.
  • Write short notes on: (A)Prodrug (B) Type-B adverse drug reaction.
Group - B
  • Enlist anxiolytic drugs. Write down the mechanism of action and indications of diazepam.
  • What do you mean by preanesthetic medication? Name the drugs used for this purpose with rationality. 
  • Enumerate the drugs use type 2 diabetes mellitus. Write dwon the role of metformin in this case. Give lisadarse effects.
  • Enumeraute the drugs used to eradicate H. pylori infection. How misoprostal protect gastrie muscosa.
  • Write down the indications of pantoprazole.
  •  What are the principal guideline for prescribng antiepileptic drugs? Mention the adverse efectes phenyton
  • White short notes on: (1) Ondansetron (2) Escitalopram
Group -C
  • Write down the biosynthesis of acetylcholine. Name the indirectly acting cholinergic drugs. Why acetylcholine is not used clinically?
  • Name the drugs with positive inotropic effect used in CCF. Discuss the role of ACE inhibitors dig heart
  • Enlist the potasium losing diuretics. Write down the mechanism of action and adverse effects of spironolactone
  • What options are available for the management of gestational hypertension? How alfa methyldopa acts Mention its adverse effects.
  • Enumerate alfa receptor blocking drugs with indications. Tamsulosin is preferred over prazocinin
  •  Write short notes on Neuromuscular blockers (0) HMG-CoA reductase inhibitors.
Group - D
  • EnList the drugs used in UTI. Mention the indications arid adverse effects of ciprofloxacin.
  • Enumerate the tissue amebildes. Outline the pharmacotheapy of amebic liver abscess.
  • Name anticoagulants used in vivo. Mention the advantages of LMWH over standard one.
  • Define and mention the criteria of essential drugs (Eds). Write down the number of Eds used in different health sector levels of our country,
  • Justify the combinations (1) Amoxicillin and clavulinic acid (i) Isoniazid and it's
  • write, short notes on: () Radical cure of malaria (0) Fluconazole.


THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2018
Subject: Pharmacology and therapeutics

Full Marks: 70 time : 2 hours 40 min


Group A
  • Define drugs uses and gives nice example or each process pharmacopeia different forway
  • Enlist four fustamine releasıng drugs write down the management of orphylactocrurierate the broncodilatars. Expaint beretici ola of salbutamol bicchiatrena,  His adverse effect
  • Define antagonist and partial agonist with examples, write down the different between regulation and downregulation of receptor.
  • Short notes on -Tolerance and Tortyphylaxis o Therapeutics window.

Group B

  • Becommemy used attery cant dugs compare and contrast between cards amerate lacel anesthetics agerts 
  • Mention the hazard reared to use kalandshetic. How the me the commercial for mutations of insulins How does stacliptin lower blood focose levet?
  • Justify the combination (ə) Levodopa and carbidopa Prednisolone and ranitidine
  • humerate the types of oral contraceptives with exaraples. Mention the mechanism of adica de
  • write short notes on Antecids Advantages of low ostrihar saline used in diarrhea.

Group -C

  • Name the Renin angiotensin aldosterone inhibitors to treat hypertension. Explain antihypertensive, mechanism of any one of them.
  • Name the antispasmodic drugs Mention the indications and adverse effects of these duos,
  • Name the diuretics used in congestive cardiac failure Explain the mechanism of action of any drug
  • Name the antichomesterase drugs Mention the pharmacological approach to manage OPC posoning with the specific role of the drugs
  • Patrate the effects of digoxin on faling heart and kidney Mention its adverse effects
  • Write short notes on- (A) Epinephrine (B) Pancuronium

Group -D

  • Enumerate five common properties of aminoglycosides, State the indications of taxone
  • Name the line antitubercular drugs with two adverse effects of each Justify the use of
  • combination of drugs on tuberculosis.Define essential drug Write down its selection criteria. 
  • Name the LMWH with indications. Mention their advantages over standard heparin,
  • What do you mean by radical cure of malaria? How it could be achieved Outline three adverse efects of chloroquine?
  • write short notes on - (A)cabies (B)Chemopropylaxis

RAJSHAHI UNIVERSITY
SECOND PROFESSIONAL MBBS (MAY)
 EXAMINATION, 2018


Group A

  • Define bioavaliability with its significance.Name the factors affecting bioavailability of drugs.
  • What are the lipid derived autacoids? Enumerate live commonly used PG analogues with their Clinical applications.
  • Mention the different inhalational drugs used to treat bronchial asthma.How do corticosteroids Act in such case.
  • Enumerate the post operative analgesics. Discuss the analgesic mechanism and adverse effects of diclofenac sodium?
  • Define receptor and classify them according to receptor action and chanel linkage with example.
  • Brefly describe the receptor mediated drug action.Order of kinetics?
  • Write short notes on Physiological & pharmacopia antagonist in drug elimination.
Group-B
  • Name the classical antipsychotics. How does haloperido act justify the use of the drug induced parkinsonism. 
  • Enumerate insulin preparation and delivery system Mention the mechanism on of metformin
  • Name the new anonusant des Outlint that of anayement to epilepticus. Mention the adverse efects of valproid.
  • Enlist olds used as SA der is reeds
  • Name the antiemetics PDF done with ondansetron relate to meet of action and adverse efects. 
  • Write short notes on Home Producent Tereps Dissociative destinas
Group - C
  • How does tamsulosin act on BHP?Write down the mechanism of action and adverses of frusemide.
  • Name the drugs without positive thotropeeds used in caldtee tallure. Explam the role of ACE inhibitors in such case
  • Classify antimuscarinic drugs with examples Categories the drugs used in glaucoma.
  • Mention the differences between nifedipine and amlodipine. Explain the antihypertensive, mechanism of these drugs.
  • Write short notes on: (A) Statins (B) Neostigmine.

Group - D

  • What do you mean by empirical antimicrobials therapy, Justify the antimicrobial combination with examples.
  • Enumerate the protein synthesis inhibitors Explain the mechanism of action and indication of erythromycin
  • List their Hazard of Irrational prescribing. Mention the steps that should be taken for rational prescribing. 
  • Enlist the blood schizonticides. Write down the therapeutic approach of chloroqume resistant falciparum malaria.
  • Name the anticoagulants used in vivo. Explain the mechanism of action and adverse effects on Warfarin
  • Write short notes on P-drug & Fluconazole

RAJSHAHI UNIVERSITY
SECOND PROFESSIONAL MBBS (November)
EXAMINATION, 2018

Subject : Pharmacology 

Group A

  • Define bioavaliability with its significance.Name the factors affecting bioavailability of drugs.
  • What are the lipid derived autacoids? Enumerate live commonly used PG analogues with their Clinical applications.
  • Mention the different inhalational drugs used to treat bronchial asthma.How do corticosteroids Act in such case.
  • Enumerate the post operative analgesics. Discuss the analgesic mechanism and adverse effects of diclofenac sodium?
  • Define receptor and classify them according to receptor action and chanel linkage with example.
  • Brefly describe the receptor mediated drug action.Order of kinetics?
  • Write short notes on Physiological & pharmacopia antagonist in drug elimination

Group-B
  • Name the classical antipsychotics. How does haloperido act justify the use of the dent drug induced parkinsonism.
  • Enumerate insulin preparation and delivery system Mention the mechanism of metformin.
  • Name the new anonusant des Outlint that of anayement to epilepticus. Mention the adverte effects of valproic acid.
  • Enlist olds used as SA der is reeds, Name the antiemetics PDF done with ondansetron relate to meet of action and adverse efects. 
  • Write short notes on Home Producent Tereps Dissociative destinas

Group - C

  • How does tamsulosin act on BHP?Write down the mechanism of action and adverses of frusemide.
  • Name the drugs without positive thotropeeds used in caldtee tallure. Explam the role of ACE inhibitors in such case
  • Classify antitiuscarinic drugs with examples Categories the drugs used in glaucoma
  • Mention the differences between nifedipine and amlodipine. Explain the antihypertensive mechanism of these drugs.
  • Write short notes on: () Statins (0 Neostigmine.

Group - D

  • What do you mean by empiric antimicrobial therapy Justify the antimicrobial combination with examples.
  • Enumerate the protein synthesis inhibitors Explain the mechanism of action and indication of erythromycin
  • List their Hazard of Irrational prescribing. Mention the steps that should be taken for rational prescribing
  • Enlist the blood schizonticides. Write down the therapeutic approach of chloroqume resistant falciparum malaria.
  • Name the anticoagulants used in vivo. Explain the mechanism of action and adverse effects on Warfarin
  • Write short notes on P-drug & Fluconazole.


RAJSHAHI MEDICAL UNIVERSITY
THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2019
Subject: Pathology


Full Marks: 70
Time: 2 hours 40 min
IN B. Marks for each question are shown in the margis. Answer any 5 (stions from each grows, USE SEPARATE ANSWER SCRIPT FOR ENCH GROUP)

Group - A

  1. What are the cellular responses to injury? Write down the differences between dystrophic and metastatic calcification.
  2. Mention types of cellular adaptation. Write dwon the advantages and disadvantages of metaplasia
  3. Write down cellular events of acute inflammation Write in brief about role of macrophages in chronic inflammation
  4. Define exudates and transudate. Outline the mechanism of oedema in cirrhosis of liver.
  5. State the morphology of malignant cell. Write a note on staging and grading of tumour.
  6.  Write short notes on: (1)Free radicals (2) Opsonins (3) Air embolism.
Group - B
  1. Classify congenital heart diseases. Mention risk factors of atherosclerosis, enumerate the complications of myocardial infarction.
  2.  Define anaemia. Give the peripheral blood film and bone marrow findings of aplastic anaemia.
  3. Mention causes of raised ESR. Write down the blood film findings of chronic myeloid leukaemia.
  4. Enumerate causes of thrombocytopenia. Name the screening rests obleeding disorder.Write a note on haemophilia.Define lymphoma. Enumerate the types of Hodgkins lymphoma Write down the differences  between Hodgkins and non-Hodgkins lymphoma.
  5. Write short notes on: ) Multiple myeloma (II) DECAL). Myeloblast.
Group-C


  1. Define peptic ulcer & mention the sites. Give the differences between Crohn's disease and ulcerative colitis,
  2. A 20 yrs old female came to you wis left lump. What are the probable causes? How will you investigate the case?
  3. Classify Bronchogenic carcinoma. Give the Laboratory diagnosis of Bronchogenic carcinoma. 
  4.  Name the germ cell tumour of the testis. Write briefly about seminoma
  5. Enumerate indications of OTT Define azospermia and pseudocyesis. How can you detect ketone bodies in urine?
  6. Write short notes on: Fixative (ii) Endometriosis () Occult blood test.
Group -D


  1. Write in brief pathogenesis of gallstone formation. What are the morphological changes in chronic cholecystitis
  2. Classify glomerular disease. Write in brief about acute diffue proliferative glomerulonephritis. 
  3. Classify germ cell tumors of the ovary. Write about Dysgerminoma,
  4. Enumerate risk factors of cervical cancer. Mention complications of leiomyoma and adenomayosis.
  5. Define & classify osteomyelitis. Give the pathogenesis & comploications of chronic osteomyelitis.
  6. Write short notes on: (1) Transformation zone (2) Basal cell carcinoma (3) Proteinuria. 


RAJSHAHI UNIVERSITY THIRD PROFESSIONAL MBBS (May) EXAMINATION, 2019 Subject: Pathology

  1. Define cell injury and necrosis and classify with example. Mention differences between necrosis and apoptosis.
  2. Write in brief about molecular basis of carcinogenesis. Give notes on atrophy and metaplasia.
  3. Mention the cardinal sign of inflamation cardinal signs of inflammation. Briefly mention reactions or blood vessels in aate 0.5+1.5+1
  4. Write about alteration in blood flow leading to thrombus formation. Write about the fate of
  5. Mention steps in the mechanism of local invasion and metasis. Enumerate common childhood tumors
  6. Write short notes on: (1) Pathogic Calcification (2) chemical carcinogens (3) Granuloma.

Group - B

  • Brierly write about pathogenesis of atherosclerosis. Enumerate ischemic heart disease. Write about angina pectoris.
  • Mention causes of pancytopenia. Briefly narrate how you are going to investigate a case of pancytopenia.
  • Define and classify leukaemia, including FAB dassification. Write down blood film and Bone marrow finding in acute myeloblastic leukaemia,
  • Classify coagulation disorders. Write in brief about idiopathic thrombocytopenic purpura,
  • Write about methods of estimation of haemoglobin. What are the information you will get after examing stained blood film.
  • Write short notes on: (1) Ascoff body (D.R-S cell (i) Leukemold reaction.
Group -C

  • Enumerate common ulcers in the GI tract, Classify salivary gland tumors. Write about 2 pleomorphic adenoma.
  • Define and classify pneumonia. Enumerate the complications of lobar pneumonia.
  • What do you mean Biopsy? Mention the tyes of biopsy. Write about fixative used in histopathology
  • Classify testiular tumors. Write in brief about teratoma & cryptochidism.
  • Classify CNS tumours. Write about hyperglycaemia sine gyepsuria.. Mention CSF findings in Pyogenic meningitis.
  • Write short notes on: (0) FNAC (0) Pap's smear (i) Papillary carcinoma of thyroid,
Group D

  • Enumerate causes of nephritic syndrome. Briefly panate pathogenesis of cervical precancer and cancers.
  • Classify bone tumors. Write about Leiomyome, Krukenberg tumour and Osteosarcoma.
  • Mention causes of abnormal uterine bleeding. Classify tumours of uterus and CIN.
  • Define and classify cirrhosis of liver. Merition pathogenesis & complications of cirrhosis of liver. 
  • Classify breast cancer and ovarian surface epithelial neoplasms.
  • Write short notes on: (1) Adenomyosis Renal function tests (2)Ewing's sarcoma.


RAJSHAHI UNIVERSITY
THIRD PROFESSIONAL MBBS (NOVEMBER) EXAMINATION, 2018
Subject: Pathology


Full Marks: 70%
Time: 2 hours 40 min
(N.B. Marks for each question are shown in the margin. Answer any 5 questions from each group. USE SEPARATE ANSWER SCRIPT FOR EACH GROUP)

Group - A

  1. Define cellular adaptation Give the difference between hyperplasia and metaplasia. Write a note on granulation tissue.
  2. Define chronic inflammation. Mention its causes. Give in brief an account the role ofcomplements in inflammation. 
  3. Define embolism and embolus. Mention types of embolus. Mention the outcome of pulmonary embolism 
  4. Mention the differences between carcinoma and sarcoma, Write a note on tumor marker.
  5. Define and classify shock. Give the pathogenesis of septic shock.
  6.  Write short notes on: (a) Hepatic congestion (b) Oncogenic viruses (c) Para neoplastic syndrome.


Group - B

  1. Classify microcytic hypochromic anemia. Write short about blood film findings of B-thalassaemia. 1+2.5
  2.  Define and classify megaloblastic anemia. Write down the blood film and bone marrow findings of megaloblastic anemia.
  3.  Define and dassify Haemorrhagic disorder, Mention causes of platelet disorders. Write abou haemophilia. 
  4. Enumerate causes of raised ESR. Mention indications and sites of bone marrow aspiration, what is anchistocyte?
  5. Mention causes of generalized lymphadenopathy, Mention types and morphology of Holdgkin's disease.Enumerate complications of MI.
  6. Write short notes on: (a) Eosinophilia (b) Myelablast (c) Atheroma.

Group -C

  1. Define peptic ulcer. Mention its site and complication. Write down differences between Crohn's disease & Ulcerative Colitis
  2. Mention types of Gall stones with its complications and pathogenesis.
  3. Classify bronchogenic carcinoma. Mention the steps you will take in the diagnosis of Bronchogenicc arcinoma.
  4. Classify germ cell tumor of Ovary. Write in brief about saeminama.
  5. Define jaundice with types. Mention the differences between types of jaundice.
  6. Write short notes on: (a) Carcinoma in situ (b) Occult blood test (c) Ketone bodies.

Group-D

  1. Classify glomerular disease. Write about acute diffuse proliferative glumerlonephritis.
  2. What do you mean by Azotaemia and ureamia? What are the clinical manifestations of renal diseases?
  3. Write about anovulatory cyde and endopmetriosis. What is Meig's syndrome?
  4. Mention causes of breast lump in a woman aged 28 yrs. How you are going to investigate the case?
  5. Define diabetes mellitus. Mention types & complications of diabetes mellitus. Give your approach to diagnose a case of Diabetes mellitus.
  6. Write short notes on: (a) Gyneacomastia (b) Fibroadenoma (c) Basal cell carcinoma.

RAJSHAHI UNIVERSITY THIRD PROFESSIONAL MBBS (May) EXAMINATION, 2018

Subject: Pathology

 Full marks: 70

  •  Define and Classify necrosis. Write in brief role of a Homeostasis and ATP depletion in causing cell injury
  • Mention differences between healing by 18 intention and 2 intention. What are the systemic factors that influences wound healing?
  • Enumerate cellular events in acute inflammation, Write a note on phagocytosis and fate of acute inflammation
  • Define thrombus. Write in brief about role of endothelium in thrombus formation. 
  • Give in brief an account of molecular basis of carcinogenesis. Write about chemical carcinogenesis.
  • Write short notes on: (a) Nutmeg liver (b) Granuloma (c) Skip metastasis

Group - B
  1. Define anaemia. Give the morphological classification of anaemia and example. Write a note on red cell indices
  2.  Define pancytopenie and mention its causes. Write down the blood film and bone marrow findings of aplastic anaemia.
  3.  Mention clinical features of anemia and leukaemia. Mention blood film findings of chronic myeloid reaction?
  4. Classify coagulation disorders. Write down the laboratory findings of ITP. Write a note on leukemoid reaction.
  5. Classify congenital heart disease. Give the pathogenesis of rheumatic fever. What is anitschow cell?
  6. Write short notes on: (a) Atherosclerosis (b) Hodgkins disease (C) E.S.R.
Group - C


  1. Classify tumors of the salivary gland. Give the morphology of pleomorphic adenoma. Why it is called pleomorphic adenoma.
  2. Define and classify Pneumonia. Mention the morphology and complications of Pneumonia.
  3. Mention pathogenesis of peptic ulcer. Give the differences between benign and malignant peptic ulcer.
  4. Write down the indications of OGTT with interpretation. Enumerate liver function tests.
  5. Mention causes of Cirrhosis of liver with pathogenesis. Write down the complications of Cirrhosis of liver.
  6. Write short notes on: (a) Cryptochidism (b) Ulcers in G.I Tract (C) Normozospermia and azospermia.
Group -D

  1. Define and mention types of Biopsy. Enumerate fixative with their aim. Write down indications of FNAC.
  2. Classify bone tumors. Write in brief about osteosarcoma and giant cell tumor of bone.
  3. Mention causes of nephritic syndrome. Write about minimal change disease and renal function tests.
  4. What is DUB? Mention causes of DUB according to age. Write about teratoma.
  5. Mention indications of CSF examination. Classify breast tumors including carcinoma breast. What is stauma ovarii?
  6. Write short notes on: (a) Hamartoma (b) Proteinuria (c) Complications of peptic ulcer and Rheumatic fever.

Third professional MBBS Examination Question Bank | Microbiology|Pharmacology| Pathology | Doctors Gang Third professional MBBS Examination Question Bank | Microbiology|Pharmacology| Pathology | Doctors Gang Reviewed by Noman Islam Nirob on Thursday, January 07, 2021 Rating: 5

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